YEATS4 and TACC2

Number of citations of the paper that reports this interaction (PubMedID 12620397)
17

Data Source:
HPRD (in vivo, in vitro)

		YEATS4	TACC2
Description		YEATS domain containing 4	transforming acidic coiled-coil containing protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding	Nuclear Hormone Receptor Binding
	Biological Process	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Proliferation Cerebral Cortex Development
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929)	Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)
Interacting Genes		13 interacting genes: CEP162 FRMD4A H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B	10 interacting genes: AURKC CREBBP EP300 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 YEATS4
Entrez ID		8089	10579
HPRD ID		03666	05600
Ensembl ID		ENSG00000127337	ENSG00000138162
Uniprot IDs		F8W0J4 O95619	B2RWP4 B7ZMJ9 D6RAA5 O95359 Q4VXL4 Q4VXL8
PDB IDs		5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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