PLEKHB2 and STAM2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLEKHB2	STAM2
Description		pleckstrin homology domain containing B2	signal transducing adaptor molecule 2
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GO Annotations	Cellular Component	Integral Component Of Membrane Recycling Endosome Membrane	Nucleoplasm Cytoplasm Cytosol Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding
	Biological Process	Regulation Of Cell Differentiation	Intracellular Protein Transport Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways			EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS			Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Metabolic syndrome ( 31170924) Pulse pressure ( 30224653)
Interacting Genes		9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1	35 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN4 USP8 VPS37C XRN1
Entrez ID		55041	10254
HPRD ID		15144	05876
Ensembl ID		ENSG00000115762	ENSG00000115145
Uniprot IDs		A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7	O75886
PDB IDs		3AJ4 3VIA	1X2Q 1X5B 2L0T 5CRV 5IXF
Enriched GO Terms of Interacting Partners?
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