PLEKHB2 and EPN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		PLEKHB2	EPN1
Description		pleckstrin homology domain containing B2	epsin 1
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GO Annotations	Cellular Component	Integral Component Of Membrane Recycling Endosome Membrane	Nucleus Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding Lipid Binding
	Biological Process	Regulation Of Cell Differentiation	In Utero Embryonic Development Endocytosis Notch Signaling Pathway Female Pregnancy Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Membrane Organization Negative Regulation Of Sprouting Angiogenesis
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			1,4-Diethylene Dioxide 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS			Major depressive disorder ( 23377640)
Interacting Genes		9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1	24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16
Entrez ID		55041	29924
HPRD ID		15144	06270
Ensembl ID		ENSG00000115762	ENSG00000063245
Uniprot IDs		A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7	A0A024R4S1 Q9Y6I3
PDB IDs		3AJ4 3VIA	1INZ 1KYD
Enriched GO Terms of Interacting Partners?
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