RHOXF2 and CRYBA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RHOXF2	CRYBA1
Description		Rhox homeobox family member 2	crystallin beta A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Night sleep phenotypes ( 27126917)
Interacting Genes		58 interacting genes: ARID5A ARMCX2 ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TENT5B TENT5C TENT5D TLE5 TMCC2 TOLLIP TRIP13 UBE2I UPF1 UTP6 VAC14 VPS25 ZBTB32	7 interacting genes: CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 RBPMS RHOXF2
Entrez ID		84528	1411
HPRD ID		02345	00429
Ensembl ID		ENSG00000131721	ENSG00000108255
Uniprot IDs		Q9BQY4	P05813
PDB IDs
Enriched GO Terms of Interacting Partners?
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