PKNOX1 and PBX2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PKNOX1	PBX2
Description		PBX/knotted 1 homeobox 1	PBX homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex Cytoplasm	Nuclear Chromatin Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding
	Biological Process	Angiogenesis Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908)
Interacting Genes		16 interacting genes: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 PCNT POU2F1 RFX3 TLX1 VPS37C ZBTB3	22 interacting genes: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 ELP1 HOXA1 HOXA9 HOXB8 MCRS1 MTREX NEU1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SMYD3 UBE2E1 ZDHHC7
Entrez ID		5316	5089
HPRD ID		03653	08890
Ensembl ID		ENSG00000160199	ENSG00000204304
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	A0A024RCR3 P40425
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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