PBX2 and MTREX

Number of citations of the paper that reports this interaction (PubMedID 14667819)
35

Data Source:
HPRD (two hybrid)

		PBX2	MTREX
Description		PBX homeobox 2	Mtr4 exosome RNA helicase
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Nuclear Speck TRAMP Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Maturation Of 5.8S RRNA RRNA Processing RNA Catabolic Process SnRNA Catabolic Process
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908)
Interacting Genes		22 interacting genes: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 ELP1 HOXA1 HOXA9 HOXB8 MCRS1 MTREX NEU1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SMYD3 UBE2E1 ZDHHC7	16 interacting genes: DIS3 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FAM107A MPHOSPH6 MPP6 PBX2 SP1 UPF2 XRN1 ZCCHC8
Entrez ID		5089	23517
HPRD ID		08890	13777
Ensembl ID		ENSG00000204304	ENSG00000039123
Uniprot IDs		A0A024RCR3 P40425	P42285 Q3MHC9
PDB IDs			6C90 6D6Q 6D6R 6IEG 6IEH 6RO1
Enriched GO Terms of Interacting Partners?
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