PBX2 and RPS6KC1

Number of citations of the paper that reports this interaction (PubMedID 14667819)
35

Data Source:
HPRD (two hybrid)

		PBX2	RPS6KC1
Description		PBX homeobox 2	ribosomal protein S6 kinase C1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Early Endosome Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol Binding
	Biological Process	Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Signal Transduction
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908)	Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430)
Interacting Genes		22 interacting genes: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 ELP1 HOXA1 HOXA9 HOXB8 MCRS1 MTREX NEU1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SMYD3 UBE2E1 ZDHHC7	3 interacting genes: PBX2 PRDX3 SPHK1
Entrez ID		5089	26750
HPRD ID		08890	10204
Ensembl ID		ENSG00000204304	ENSG00000136643
Uniprot IDs		A0A024RCR3 P40425	A0A087X1U5 F5H7T0 F6RJM5 Q96S38
PDB IDs
Enriched GO Terms of Interacting Partners?
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