PKNOX1 and ZBTB3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PKNOX1	ZBTB3
Description		PBX/knotted 1 homeobox 1	zinc finger and BTB domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex Cytoplasm	Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Angiogenesis Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Cellular Response To DNA Damage Stimulus
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: APP HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 PAX6 PBX1 PBX2 PCNT POU2F1 RFX3 TLX1 VPS37C ZBTB3	21 interacting genes: ANKRD2 BIN1 EIF5B FOXM1 GATA4 GTF2A1L IKBKG IRF6 JADE2 LEF1 NR3C1 PKNOX1 PPARG PROX1 SKIL SMAD3 SSX3 SUPT5H THRA ZMYM2 ZNF556
Entrez ID		5316	79842
HPRD ID		03653	15693
Ensembl ID		ENSG00000160199	ENSG00000185670
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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