NLK and ASGR1

Number of citations of the paper that reports this interaction (PubMedID 18624398)
14

Data Source:
BioGRID (two hybrid)

		NLK	ASGR1
Description		nemo like kinase	asialoglycoprotein receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Metal Ion Binding
	Biological Process	MAPK Cascade Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Regulation Of Gene Expression Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Serine Phosphorylation Of STAT Protein Protein Autophosphorylation Protein Stabilization	Receptor-mediated Endocytosis Viral Process Protein N-linked Glycosylation Via Asparagine Cellular Response To Extracellular Stimulus
Pathways		Ca2+ pathway	Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Non-response to bupropion and depression ( 27622933)	Liver enzyme levels (alkaline phosphatase) ( 22001757) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 31666285 29403010)
Interacting Genes		23 interacting genes: ASGR1 ATXN1 CREBBP CUL1 FBXW5 FOXO4 FOXP3 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 QRICH1 RCHY1 SDR16C5 SKP2 STAT3 USP4 ZHX3	14 interacting genes: APP ASGR2 CERS2 CLEC4G DHFR HIVEP1 HSP90AA1 HSP90B1 LAMTOR5 LMNA NLK RBBP6 TG VKORC1
Entrez ID		51701	432
HPRD ID		17637	00151
Ensembl ID		ENSG00000087095	ENSG00000141505
Uniprot IDs		A0A024QZ12 Q9UBE8	P07306 Q6FGQ5
PDB IDs			1DV8 5JPV 5JQ1
Enriched GO Terms of Interacting Partners?
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