NLK and KRTAP4-2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NLK	KRTAP4-2
Description		nemo like kinase	keratin associated protein 4-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytosol Keratin Filament
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding	Protein Binding
	Biological Process	MAPK Cascade Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Regulation Of Gene Expression Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Serine Phosphorylation Of STAT Protein Protein Autophosphorylation Protein Stabilization	Keratinization
Pathways		Ca2+ pathway	Keratinization
Drugs
Diseases
GWAS		Non-response to bupropion and depression ( 27622933)
Interacting Genes		23 interacting genes: ASGR1 ATXN1 CREBBP CUL1 FBXW5 FOXO4 FOXP3 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 QRICH1 RCHY1 SDR16C5 SKP2 STAT3 USP4 ZHX3	75 interacting genes: ADAMTSL4 ALDH3B1 AMOTL2 AQP1 ATG9A AXIN1 BYSL CHIC2 CHRD CRCT1 CREB5 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT HOXA1 HPCAL1 HSD3B7 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LASP1 LCE1B LCE2A LCE3C LCE3E LCE4A LNX1 MEOX2 NECTIN3 NLK NOTCH2NLA NR1D2 NTAQ1 NUFIP2 OTX1 PDE9A PGLS PIN1 PLSCR1 POM121L8P PRKAB2 PRKAG1 PSMA6 RASSF5 RGS20 SDC3 SHFL SLC23A1 SLC25A10 SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581 ZNF688
Entrez ID		51701	85291
HPRD ID		17637	13944
Ensembl ID		ENSG00000087095	ENSG00000244537
Uniprot IDs		A0A024QZ12 Q9UBE8	Q9BYR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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