TIMMDC1 and FATE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TIMMDC1	FATE1
Description		translocase of inner mitochondrial membrane domain containing 1	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Primary biliary cholangitis ( 30643196) Primary biliary cirrhosis ( 22961000) Systemic lupus erythematosus ( 28714469) Systemic sclerosis ( 31672989)	Systemising ( 31508503)
Interacting Genes		3 interacting genes: APP FATE1 HGS	57 interacting genes: AGTRAP AQP9 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC70 CD302 CD79A CSF2RA CXCR3 DCTN5 EMD GPR25 INPP5K KASH5 KCNS2 LMNA LNPEP MARCHF2 MARCHF5 MR1 NDUFB11 NRG4 NRSN1 OCLN PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SMIM14 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF2 YIPF4
Entrez ID		51300	89885
HPRD ID		12817	02346
Ensembl ID		ENSG00000113845	ENSG00000147378
Uniprot IDs		C9JU35 Q9NPL8	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?
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