ZNF277 and GNGT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF277	GNGT1
Description		zinc finger protein 277	G protein subunit gamma transducin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Photoreceptor Inner Segment Heterotrimeric G-protein Complex Plasma Membrane G-protein Beta/gamma-subunit Complex Photoreceptor Disc Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Metal Ion Binding	GTPase Activity Protein Binding G-protein Beta-subunit Binding
	Biological Process	Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence	Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Localization Cardiac Muscle Cell Apoptotic Process Rhodopsin Mediated Signaling Pathway Eye Photoreceptor Cell Development Cellular Response To Hypoxia
Pathways			Activation of G protein gated Potassium channels G-protein activation Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Olfactory Signaling Pathway ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Breast size ( 22747683) Early-onset Parkinson's disease ( 28256260)	Body mass index ( 28552196) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mosquito bite size ( 28199695) Resting heart rate ( 29769521 27798624) Taxane-induced peripheral neuropathy in breast cancer ( 29278617)
Interacting Genes		7 interacting genes: COIL DDB1 GNGT1 MBD3 NUTM1 ZBTB7B ZNF768	11 interacting genes: GNAS GNB1 GNB2 GNB4 GNB5 IKBKG NAGA PDCL PLEKHB1 RHO ZNF277
Entrez ID		11179	2792
HPRD ID		05680	01805
Ensembl ID		ENSG00000198839	ENSG00000127928
Uniprot IDs		Q9NRM2	P63211
PDB IDs
Enriched GO Terms of Interacting Partners?
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