WASHC3 and KRT6A

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WASHC3	KRT6A
Description		WASH complex subunit 3	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome WASH Complex	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Exocytosis Biological_process Protein Transport Actin Filament Polymerization	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		29 interacting genes: ABI2 BLOC1S6 CCHCR1 CEP55 CKAP4 DTNBP1 GDF9 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 KDM1A KRT6A LAMC1 LUC7L2 MCRS1 MOB1B NDC80 NUP62 OPTN PBXIP1 PCM1 PTN SDCBP SNAP25 SYCE1 TXLNA TXLNB	22 interacting genes: CCDC85B DSP GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT31 KRT38 KRT40 LMNA MTUS2 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 WASHC3
Entrez ID		51019	3853
HPRD ID		13031	01011
Ensembl ID		ENSG00000120860	ENSG00000205420
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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