KRT6A and KRT13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		KRT6A	KRT13
Description		keratin 6A	keratin 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	Cytoskeleton Organization Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex	White sponge nevus
GWAS
Interacting Genes		22 interacting genes: CCDC85B DSP GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT31 KRT38 KRT40 LMNA MTUS2 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 WASHC3	52 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GOLGA8EP GRAP2 HGS IFT20 KLC3 KLC4 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT79 KRT8 LSM2 MOS MYH1 NEFL PPP1R18 PSMB1 PSMB2 RTL8B SGF29 TLE5 TMSB4X TRIM42 TSG101 TXLNA ZNF688
Entrez ID		3853	3860
HPRD ID		01011	01016
Ensembl ID		ENSG00000205420	ENSG00000171401
Uniprot IDs		A0A0S2Z428 P02538	A1A4E9 P13646
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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