KRT6A and KRT17

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT6A	KRT17
Description		keratin 6A	keratin 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Intermediate Filament Cytoskeleton Extracellular Exosome Cell Periphery
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding MHC Class II Receptor Activity MHC Class II Protein Binding
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	Signal Transduction Epidermis Development Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex	Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		22 interacting genes: CCDC85B DSP GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT31 KRT38 KRT40 LMNA MTUS2 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 WASHC3	10 interacting genes: APC CCDC85B EGFR HRAS KDM1A KRT6A KRT7 KRT72 TRIM69 ZDHHC17
Entrez ID		3853	3872
HPRD ID		01011	01019
Ensembl ID		ENSG00000205420	ENSG00000128422
Uniprot IDs		A0A0S2Z428 P02538	Q04695 Q14666
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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