KRT6A and KIFC3

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		KRT6A	KIFC3
Description		keratin 6A	kinesin family member C3
Image
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed ATPase Activity
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		22 interacting genes: CCDC85B DSP GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT31 KRT38 KRT40 LMNA MTUS2 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 WASHC3	93 interacting genes: ABI2 ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CBY2 CCDC102B CCDC136 CCDC28A CCDC33 CDK18 CDR2 CEP55 CEP57L1 CLIP4 COG7 CREB5 CYTH4 DCTN2 DCX DEUP1 DTNBP1 ESRRG FAM124A FANCL FBXO7 FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SVIL SYCE1 TCEANC TLE5 TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655 ZNF688
Entrez ID		3853	3801
HPRD ID		01011	05171
Ensembl ID		ENSG00000205420	ENSG00000140859
Uniprot IDs		A0A0S2Z428 P02538	B7Z5U4 B7Z808 B7Z896 F5H3M2 Q9BVG8
PDB IDs		5KI0	5WDE
Enriched GO Terms of Interacting Partners?
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