SHANK1 and ARHGEF7

  • Number of citations of the paper that reports this interaction (PubMedID 12626503)
  • 61
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vitro, two hybrid, in vivo)

SHANK1

ARHGEF7

Description SH3 and multiple ankyrin repeat domains 1 Rho guanine nucleotide exchange factor 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clozapine-induced cytotoxicity ( 25656473)
  • Bilirubin levels ( 19414484)
  • Choroid plexus volume ( 31530798)
  • Fasting insulin (dietary factor interaction) ( 24204828)
  • Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
  • Macular thickness ( 30535121)
  • Menarche (age at onset) ( 21102462)
  • Menopause (age at onset) ( 19448619)
  • Skin aging measurement ( 31522824)
Interacting Genes 18 interacting genes: ABCA1 ADGRB2 ADGRL1 ADGRL2 ARHGEF7 BAIAP2 DLG4 DLGAP1 DNM2 HOMER1 RPS6KA2 RPS6KA3 SHARPIN SPTAN1 SSTR2 STAT1 TANC1 USP8 33 interacting genes: ADAM15 ARHGEF6 CALM1 CBLB CD244 CDC42 EGFR ERBIN GIT1 GIT2 HSPB1 ITCH LRRK2 MEOX2 NCK1 NCKIPSD NOX1 PAK1 PAK2 PAK3 PPM1E PPM1F PRKCG PXN RAC1 SCRIB SH2D1A SHANK1 SHANK2 TGFBR2 TUBB3 WAS YWHAG
Entrez ID 50944 8874
HPRD ID 05413 05688
Ensembl ID ENSG00000161681 ENSG00000102606
Uniprot IDs H9KV90 Q9Y566 A0A024RDY9 B7Z344 B7Z6G2 E9PDQ5 Q14155 Q5W9H1
PDB IDs 6CPI 1BY1 1ZSG 2L3G 5SXP
Enriched GO Terms of Interacting Partners?
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