MTREX and MPP6

Number of citations of the paper that reports this interaction (PubMedID 11719186)
341

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		MTREX	MPP6
Description		Mtr4 exosome RNA helicase	membrane palmitoylated protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Nuclear Speck TRAMP Complex Catalytic Step 2 Spliceosome	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Maturation Of 5.8S RRNA RRNA Processing RNA Catabolic Process SnRNA Catabolic Process	Protein-containing Complex Assembly
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fasting glucose change (long-term) ( 31263163) Schizophrenia ( 29483656) Urate levels in obese individuals ( 25811787)
Interacting Genes		16 interacting genes: DIS3 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FAM107A MPHOSPH6 MPP6 PBX2 SP1 UPF2 XRN1 ZCCHC8	28 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		23517	51678
HPRD ID		13777	09509
Ensembl ID		ENSG00000039123	ENSG00000105926
Uniprot IDs		P42285 Q3MHC9	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		6C90 6D6Q 6D6R 6IEG 6IEH 6RO1
Enriched GO Terms of Interacting Partners?
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