NTRK2 and SHC3

  • Number of citations of the paper that reports this interaction (PubMedID 9507002)
  • 22
  • Data Source:
  • HPRD (in vivo)

NTRK2

SHC3

Description neurotrophic receptor tyrosine kinase 2 SHC adaptor protein 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Birth weight ( 24950379)
  • Body mass index ( 28892062 25760438)
  • Lifetime anxiety disorder ( 31748690)
  • Menarche (age at onset) ( 25231870)
  • Serum metabolite concentrations in chronic kidney disease ( 29545352)
  • Type 2 diabetes ( 31118516)
  • Waist-to-hip circumference ratio (recreational physical activity interaction) ( 23192594)
  • Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Superior parietal cortex volume ( 31530798)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 33 interacting genes: AP1B1 BDNF DOK5 DYNLL1 EGFR ERBB2 ERBB4 FRS2 FRS3 FYN GIPC1 KIDINS220 NCK1 NCK2 NDFIP1 NGFR NMNAT1 NTF3 NTF4 PIK3R1 PLCG1 POLR2G PTPN1 PTPN11 RASGRF1 SH2B1 SH2B2 SHC1 SHC2 SHC3 SQSTM1 TRAF6 UBB 16 interacting genes: ALK APP ARHGAP32 AXL EGFR ERBB2 ERBB3 FLT4 GOLGA2 GRB2 KRT31 KRT40 NTRK1 NTRK2 RET SH3GL3
Entrez ID 4915 53358
HPRD ID 02712 12005
Ensembl ID ENSG00000148053 ENSG00000148082
Uniprot IDs A0A024R230 Q16620 Q548C2 Q5VWE5 Q92529
PDB IDs 1HCF 1WWB 2MFQ 4ASZ 4AT3 4AT4 4AT5 5MO9
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?