NTRK2 and NCK1

  • Number of citations of the paper that reports this interaction (PubMedID 12074588)
  • 5
  • Data Source:
  • HPRD (two hybrid)

NTRK2

NCK1

Description neurotrophic receptor tyrosine kinase 2 NCK adaptor protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Birth weight ( 24950379)
  • Body mass index ( 28892062 25760438)
  • Lifetime anxiety disorder ( 31748690)
  • Menarche (age at onset) ( 25231870)
  • Serum metabolite concentrations in chronic kidney disease ( 29545352)
  • Type 2 diabetes ( 31118516)
  • Waist-to-hip circumference ratio (recreational physical activity interaction) ( 23192594)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Blood urea nitrogen levels ( 31152163)
  • Body mass index ( 25673413)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 33 interacting genes: AP1B1 BDNF DOK5 DYNLL1 EGFR ERBB2 ERBB4 FRS2 FRS3 FYN GIPC1 KIDINS220 NCK1 NCK2 NDFIP1 NGFR NMNAT1 NTF3 NTF4 PIK3R1 PLCG1 POLR2G PTPN1 PTPN11 RASGRF1 SH2B1 SH2B2 SHC1 SHC2 SHC3 SQSTM1 TRAF6 UBB 86 interacting genes: ABI1 ABI2 ABL1 ADAM15 ADGRL2 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CRK CSNK1G2 CYFIP2 DAG1 DCC DNM1 DOK1 DOK2 DRD3 DRD4 EFS EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB3 FASLG FCHO1 FGFR1 FLT1 FLT3 FRS2 GAB2 GMPPA HOMEZ KDR KHDRBS1 KIAA1522 LCP2 MAP4K1 MAP4K4 MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NPHS1 NTRK2 NUTM2F OLIG1 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PIK3R3 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SH2D1A SHANK3 SOCS1 SOCS7 SORBS3 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1
Entrez ID 4915 4690
HPRD ID 02712 02740
Ensembl ID ENSG00000148053 ENSG00000158092
Uniprot IDs A0A024R230 Q16620 Q548C2 Q5VWE5 A0A0S2Z4Y3 P16333
PDB IDs 1HCF 1WWB 2MFQ 4ASZ 4AT3 4AT4 4AT5 5MO9 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4
Enriched GO Terms of Interacting Partners?
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