SHC3

Description		SHC adaptor protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol Plasma Membrane Synapse
	Molecular Function	Phosphotyrosine Residue Binding Protein Binding Protein Kinase Binding Receptor Tyrosine Kinase Binding
	Biological Process	MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Axon Guidance Central Nervous System Development Learning Or Memory Synaptic Transmission, Glutamatergic
Pathways		Signalling to RAS Signalling to RAS RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Pelvic organ prolapse (moderate/severe) ( 26545240) Response to statins (LDL cholesterol change) ( 22331829) Superior parietal cortex volume ( 31530798) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		16 interacting genes: ALK APP ARHGAP32 AXL EGFR ERBB2 ERBB3 FLT4 GOLGA2 GRB2 KRT31 KRT40 NTRK1 NTRK2 RET SH3GL3
Entrez ID		53358
HPRD ID		12005
Ensembl ID		ENSG00000148082
Uniprot IDs		Q92529
PDB IDs
Enriched GO Terms of Interacting Partners?
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