U2AF1 and RNPS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		U2AF1	RNPS1
Description		U2 small nuclear RNA auxiliary factor 1	RNA binding protein with serine rich domain 1
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blood and toenail selenium levels ( 25343990)
Interacting Genes		38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2	34 interacting genes: CHERP CLK2 DVL2 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKTR PIN1 PNN PRPF38A RBM8A SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRSF1 SRSF11 SRSF4 SRSF6 TAF2 TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YWHAB YWHAG ZBTB14 ZNF473 ZNF490
Entrez ID		7307	10921
HPRD ID		01871	07341
Ensembl ID		ENSG00000160201	ENSG00000205937
Uniprot IDs		P0DN76 Q01081 Q7Z780	D3DU92 H3BMS0 Q15287
PDB IDs		1JMT	4A8X
Enriched GO Terms of Interacting Partners?
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