NCK1 and LCP2

  • Number of citations of the paper that reports this interaction (PubMedID 10229072)
  • 32
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

NCK1

LCP2

Description NCK adaptor protein 1 lymphocyte cytosolic protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Blood urea nitrogen levels ( 31152163)
  • Body mass index ( 25673413)
  • Schizophrenia ( 25056061 29483656)
  • Acne (severe) ( 24927181)
  • Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes 86 interacting genes: ABI1 ABI2 ABL1 ADAM15 ADGRL2 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CRK CSNK1G2 CYFIP2 DAG1 DCC DNM1 DOK1 DOK2 DRD3 DRD4 EFS EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB3 FASLG FCHO1 FGFR1 FLT1 FLT3 FRS2 GAB2 GMPPA HOMEZ KDR KHDRBS1 KIAA1522 LCP2 MAP4K1 MAP4K4 MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NPHS1 NTRK2 NUTM2F OLIG1 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PIK3R3 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SH2D1A SHANK3 SOCS1 SOCS7 SORBS3 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1 43 interacting genes: APP BLNK CBL CD22 CLNK EGFR FXR2 FYB1 FYN GOLGA2 GRAP2 GRB2 HCK ITK LARP1 LAT LCK LMNA LYN MAP4K1 NCK1 NCK2 PAG1 PJA1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAE YWHAZ ZAP70
Entrez ID 4690 3937
HPRD ID 02740 03362
Ensembl ID ENSG00000158092 ENSG00000043462
Uniprot IDs A0A0S2Z4Y3 P16333 Q13094
PDB IDs 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4 1H3H 1YWO 2EAP 2ROR
Enriched GO Terms of Interacting Partners?
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