MTF1 and AP1M1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MTF1	AP1M1
Description		metal regulatory transcription factor 1	adaptor related protein complex 1 subunit mu 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Histone Acetyltransferase Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Central Nervous System Development Response To Metal Ion Positive Regulation Of Transcription By RNA Polymerase II Response To Cadmium Ion Cellular Response To Zinc Ion Cartilage Homeostasis	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) MTF1 activates gene expression MTF1 activates gene expression	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hypothyroidism ( 27182965 22493691) Pulse pressure ( 27841878) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		2 interacting genes: AP1M1 PABPC4	47 interacting genes: AKAP8L AP1M2 AP2B1 ARFRP1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ENTR1 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SELP SLC2A4 SRPK2 SSX2IP TGOLN2 TIFA TNIP1 VAMP4 VANGL2 ZBTB14 ZBTB43 ZBTB44 ZBTB8A
Entrez ID		4520	8907
HPRD ID		02546	04639
Ensembl ID		ENSG00000188786	ENSG00000072958
Uniprot IDs		Q14872	A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?
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