VCAM1 and ITGB7

Number of citations of the paper that reports this interaction (PubMedID 12682249)
10

Data Source:
HPRD (in vitro)

		VCAM1	ITGB7
Description		vascular cell adhesion molecule 1	integrin subunit beta 7
Image
GO Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Exosome
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Amine Metabolic Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of T Cell Proliferation Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Interferon-gamma-mediated Signaling Pathway Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Viral Entry Into Host Cell Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions
Drugs		Ethanol Carvedilol Succinobucol	R1295 Vedolizumab
Diseases
GWAS		Multiple sclerosis ( 31604244 24076602 21833088) SjÃ¶gren's syndrome ( 24097067)	Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN USP2	15 interacting genes: CDH1 DAB1 DOK1 EED FLNA FN1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD RACK1 TLN1 TNS2 VCAM1
Entrez ID		7412	3695
HPRD ID		01888	00948
Ensembl ID		ENSG00000162692	ENSG00000139626
Uniprot IDs		P19320	P26010
PDB IDs		1IJ9 1VCA 1VSC	2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?
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