VCAM1 and ITGAD

Number of citations of the paper that reports this interaction (PubMedID 10438935)
29

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		VCAM1	ITGAD
Description		vascular cell adhesion molecule 1	integrin subunit alpha D
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Plasma Membrane Integrin Complex Cell Surface
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Metal Ion Binding
	Biological Process	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Amine Metabolic Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of T Cell Proliferation Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Interferon-gamma-mediated Signaling Pathway Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling	Integrin cell surface interactions
Drugs		Ethanol Carvedilol Succinobucol
Diseases
GWAS		Multiple sclerosis ( 31604244 24076602 21833088) SjÃ¶gren's syndrome ( 24097067)	Mean corpuscular hemoglobin ( 27863252) Red cell distribution width ( 27863252)
Interacting Genes		13 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN USP2	4 interacting genes: ICAM3 ITGB2 SHARPIN VCAM1
Entrez ID		7412	3681
HPRD ID		01888	11785
Ensembl ID		ENSG00000162692	ENSG00000156886
Uniprot IDs		P19320	Q13349 Q59H14
PDB IDs		1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?
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