MXD1 and SAP30

Number of citations of the paper that reports this interaction (PubMedID 7889570)
189

Data Source:
HPRD (in vitro, in vivo)

		MXD1	SAP30
Description		MAX dimerization protein 1	Sin3A associated protein 30
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion Cytosol	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Dimerization Activity	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 27863252) Mean platelet volume ( 27863252) Platelet count ( 27863252) Red cell distribution width ( 28957414)
Interacting Genes		19 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MOGS MYC MYCL MYCN PML PRAM1 RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		4084	8819
HPRD ID		02487	04540
Ensembl ID		ENSG00000059728	ENSG00000164105
Uniprot IDs		B7ZLI7 Q05195	O75446
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q	2KDP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?