LNPEP and FATE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LNPEP	FATE1
Description		leucyl and cystinyl aminopeptidase	fetal and adult testis expressed 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Early Endosome Lumen Perinuclear Region Of Cytoplasm	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane
	Molecular Function	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Protein Catabolic Process Peptide Catabolic Process SMAD Protein Signal Transduction Negative Regulation Of Cold-induced Thermogenesis	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways		Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)	Systemising ( 31508503)
Interacting Genes		8 interacting genes: FATE1 FHOD1 REL SLC2A4 SMAD9 TCF4 TNKS TNKS2	57 interacting genes: AGTRAP AQP9 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC70 CD302 CD79A CSF2RA CXCR3 DCTN5 EMD GPR25 INPP5K KASH5 KCNS2 LMNA LNPEP MARCHF2 MARCHF5 MR1 NDUFB11 NRG4 NRSN1 OCLN PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SMIM14 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF2 YIPF4
Entrez ID		4012	89885
HPRD ID		01041	02346
Ensembl ID		ENSG00000113441	ENSG00000147378
Uniprot IDs		Q9UIQ6	Q969F0
PDB IDs		4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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