LAMC1 and NID1

Number of citations of the paper that reports this interaction (PubMedID 9733643)
69

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		LAMC1	NID1
Description		laminin subunit gamma 1	nidogen 1
Image
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-1 Complex Extracellular Space Endoplasmic Reticulum Lumen Laminin-10 Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Basement Membrane Plasma Membrane Receptor Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Constituent Conferring Elasticity	Extracellular Matrix Structural Constituent Calcium Ion Binding Collagen Binding Wnt-protein Binding Wnt-activated Receptor Activity Laminin Binding Laminin-1 Binding Proteoglycan Binding
	Biological Process	Cell Adhesion Endoderm Development Animal Organ Morphogenesis Tissue Development Cell Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Hemidesmosome Assembly Substrate Adhesion-dependent Cell Spreading Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Protein-containing Complex Assembly	Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Glomerular Basement Membrane Development Canonical Wnt Signaling Pathway Basement Membrane Organization
Pathways		Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation EGR2 and SOX10-mediated initiation of Schwann cell myelination	Degradation of the extracellular matrix Degradation of the extracellular matrix Laminin interactions Laminin interactions
Drugs			Urokinase
Diseases
GWAS		Blood protein levels ( 29875488) Clozapine-induced agranulocytosis ( 25187353) Colorectal cancer ( 23266556) Colorectal cancer or advanced adenoma ( 30510241) Diastolic blood pressure ( 30224653) Fuchs's corneal dystrophy ( 28358029) Height ( 31562340) Hypertriglyceridemia ( 27599772) Systemic lupus erythematosus ( 24871463)	Blood protein levels ( 30072576) Cutaneous nevi ( 21478494) Diverticulitis ( 28585551) Urate levels in overweight individuals ( 25811787)
Interacting Genes		14 interacting genes: ANTXR2 APP ATF7IP CENPU LAMA5 NID1 NID2 PSMC5 SNAPIN SNX2 SRPK1 TANK UBC WASHC3	21 interacting genes: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL
Entrez ID		3915	4811
HPRD ID		01030	00574
Ensembl ID		ENSG00000135862	ENSG00000116962
Uniprot IDs		P11047 Q6NVY8	P14543
PDB IDs		5XAU	1NDX
Enriched GO Terms of Interacting Partners?
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