TCHP and KRT5

Number of citations of the paper that reports this interaction (PubMedID 15731015)
3

Data Source:
HPRD (two hybrid)

		TCHP	KRT5
Description		trichoplein keratin filament binding	keratin 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex Ciliary Transition Fiber	Nucleus Cytoplasm Cytosol Intermediate Filament Plasma Membrane Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly	Cytoskeleton Organization Epidermis Development Keratinization Hemidesmosome Assembly Cornification
Pathways			Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs			Zinc
Diseases			Dowling-Degos disease Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Basal cell carcinoma ( 31174203 24403052 25855136 27539887) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		23 interacting genes: CCDC172 CCDC85B CDR2 DYDC1 IFFO1 KCTD17 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM	17 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL KIFC3 KRT1 KRT14 KRT15 KRT18 KRT31 KRT38 KRT40 PKP2 TCHP UBE3A
Entrez ID		84260	3852
HPRD ID		14403	01010
Ensembl ID		ENSG00000139437	ENSG00000186081
Uniprot IDs		A0A024RBM9 Q9BT92	P13647
PDB IDs			3TNU
Enriched GO Terms of Interacting Partners?
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