KIT and SOCS6

  • Number of citations of the paper that reports this interaction (PubMedID 14707129)
  • 23
  • Data Source:
  • BioGRID (x-ray crystallography)
  • HPRD (two hybrid, in vitro, in vivo)

KIT

SOCS6

Description KIT proto-oncogene, receptor tyrosine kinase suppressor of cytokine signaling 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 60 interacting genes: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF1R CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R ILKAP INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN20 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B STYX TEC YES1 31 interacting genes: ACVR1 APPL1 BMPR1B CLNK CRK DAB1 EFEMP1 EGFR ELOB ELOC FRS3 INSR IRS2 IRS4 KDM1A KIT LNX1 PIK3R1 PIK3R2 PIK3R3 PITRM1 RBCK1 RELA SMURF2 TGFBR1 TUBA1A TUBB4B UBE2D2 UBE2I WDR89 ZMIZ2
Entrez ID 3815 9306
HPRD ID 01287 05491
Ensembl ID ENSG00000157404 ENSG00000170677
Uniprot IDs A0A0U2N547 P10721 A0A024R379 O14544
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2IUH 2VIF 3G0E 3G0F 4HVS 4K94 4K9E 4PGZ 4U0I 6GQJ 6GQK 6GQL 6GQM 6HH1 6ITT 6ITV 6KLA 6MOB 2VIF
Enriched GO Terms of Interacting Partners?
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