SOCS6 and WDR89

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SOCS6	WDR89
Description		suppressor of cytokine signaling 6	WD repeat domain 89
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Cytosol Phosphatidylinositol 3-kinase Complex
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Defense Response JAK-STAT Cascade Negative Regulation Of Signal Transduction Proteasomal Protein Catabolic Process Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Phosphatidylinositol Phosphorylation Negative Regulation Of T Cell Activation	Ventricular System Development Corpus Callosum Development
Pathways		Regulation of KIT signaling Neddylation
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) Night sleep phenotypes ( 27126917) Systemic lupus erythematosus ( 18204098) Type 2 diabetes ( 29621232)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		31 interacting genes: ACVR1 APPL1 BMPR1B CLNK CRK DAB1 EFEMP1 EGFR ELOB ELOC FRS3 INSR IRS2 IRS4 KDM1A KIT LNX1 PIK3R1 PIK3R2 PIK3R3 PITRM1 RBCK1 RELA SMURF2 TGFBR1 TUBA1A TUBB4B UBE2D2 UBE2I WDR89 ZMIZ2	5 interacting genes: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		9306	112840
HPRD ID		05491	12635
Ensembl ID		ENSG00000170677	ENSG00000140006
Uniprot IDs		A0A024R379 O14544	A0A024R667 Q96FK6
PDB IDs		2VIF
Enriched GO Terms of Interacting Partners?
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