JAK3 and SOCS3

  • Number of citations of the paper that reports this interaction (PubMedID 10373548)
  • 51
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

JAK3

SOCS3

Description Janus kinase 3 suppressor of cytokine signaling 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
  • Creatine kinase levels ( 29403010)
Interacting Genes 43 interacting genes: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK LNX1 PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC RAB8A SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 54 interacting genes: ABL1 ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR ELOB ELOC EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRF7 IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RNF7 RPL7A SH2D2A SOCS2 TES TFDP1 TFR2 TRDN TXNDC11 YES1 YWHAQ
Entrez ID 3718 9021
HPRD ID 02547 05006
Ensembl ID ENSG00000105639 ENSG00000184557
Uniprot IDs A0A024R7M7 P52333 O14543 Q6FI39
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 3ZEP 4HVD 4HVG 4HVH 4HVI 4I6Q 4QPS 4QT1 4RIO 4V0G 4Z16 5LWM 5LWN 5TOZ 5TTS 5TTU 5TTV 5VO6 5W86 5WFJ 6AAK 6DA4 6DB3 6DB4 6DUD 6GL9 6GLA 6GLB 6HZV 6NY4
Enriched GO Terms of Interacting Partners?
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