SOCS3 and RBMX

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SOCS3	RBMX
Description		suppressor of cytokine signaling 3	RNA binding motif protein X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Phosphatidylinositol 3-kinase Complex	Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Nuclear Euchromatin Membrane Protein-containing Complex Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Phosphotyrosine Residue Binding Protein Kinase Inhibitor Activity Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity JAK-STAT Cascade Protein Ubiquitination Cytokine-mediated Signaling Pathway Intracellular Signal Transduction Regulation Of Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Apoptotic Process Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Positive Regulation Of Cell Differentiation Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Negative Regulation Of Inflammatory Response Regulation Of Interferon-gamma-mediated Signaling Pathway Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Trophoblast Giant Cell Differentiation Spongiotrophoblast Differentiation Interleukin-6-mediated Signaling Pathway Cellular Response To Leukemia Inhibitory Factor	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Splice Site Selection Membrane Protein Ectodomain Proteolysis RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Protein Homooligomerization Cellular Response To Interleukin-1
Pathways		Interleukin-6 signaling Signaling by Leptin Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling Regulation of IFNG signaling PTK6 Activates STAT3 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Neddylation Interferon alpha/beta signaling Regulation of IFNA signaling Growth hormone receptor signaling Antigen processing: Ubiquitination & Proteasome degradation	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Creatine kinase levels ( 29403010)	Pediatric autoimmune diseases ( 26301688)
Interacting Genes		54 interacting genes: ABL1 ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR ELOB ELOC EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRF7 IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RNF7 RPL7A SH2D2A SOCS2 TES TFDP1 TFR2 TRDN TXNDC11 YES1 YWHAQ	37 interacting genes: APOBEC3C CCDC33 CIRBP CLK1 CLK3 CSNK2A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LNX1 MAGOHB NABP1 NFE2L2 PRPF31 PRR3 PSMF1 RAMAC RBM3 RBM7 RBMY1A1 RBMY1F ROBO3 SNRPA SOCS3 SORBS3 SREK1 SRPK2 STAT5A TRA2B XRN1 ZNF490
Entrez ID		9021	27316
HPRD ID		05006	02186
Ensembl ID		ENSG00000184557	ENSG00000147274
Uniprot IDs		O14543 Q6FI39	P38159
PDB IDs			2MB0 2MKS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?