ITGB2 and NUMB

  • Number of citations of the paper that reports this interaction (PubMedID 12606711)
  • 115
  • Data Source:
  • HPRD (in vitro)

ITGB2

NUMB

Description integrin subunit beta 2 NUMB endocytic adaptor protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 31194737)
Interacting Genes 45 interacting genes: C3 CD14 CD226 CD82 CHPF COPS3 COPS5 CYTH1 CYTH2 DAB1 DOK1 EGFR ESM1 FCER2 FHL2 FUT4 HP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ILK ITGAD ITGAM ITGAX KNG1 NOTCH2NLA NUMB PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRTN3 PTK2 PTK2B RACK1 RANBP9 RDX SHARPIN SYK TLN1 VNN2 33 interacting genes: AP2A1 AP2A2 APP DNAJC5 DPYSL2 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 TERF2
Entrez ID 3689 8650
HPRD ID 02506 04767
Ensembl ID ENSG00000160255 ENSG00000133961
Uniprot IDs A0A494C0X7 B4E0R1 P05107 A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757
PDB IDs 1JX3 1L3Y 1YUK 2JF1 2P26 2P28 2V7D 3K6S 3K71 3K72 4NEH 4NEN 5E6R 5E6S 5E6U 5E6V 5E6W 5E6X 5ES4 5XR1 5ZAZ 5NJJ 5NJK
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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