NUMB and PRKCZ

  • Number of citations of the paper that reports this interaction (PubMedID 17203073)
  • 91
  • Data Source:
  • BioGRID (enzymatic study, pull down)
  • HPRD (in vitro)

NUMB

PRKCZ

Description NUMB endocytic adaptor protein protein kinase C zeta
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 31194737)
  • Body mass index ( 26426971)
  • General risk tolerance (MTAG) ( 30643258)
  • Height ( 20881960)
  • Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)
Interacting Genes 33 interacting genes: AP2A1 AP2A2 APP DNAJC5 DPYSL2 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 TERF2 88 interacting genes: ADAP1 ADCY5 AFAP1 AKT1 AKT3 BLVRA BTK C1QBP CASP3 CASP6 CASP7 CASP8 CASP9 CCDC115 CDC42 CHAT CSNK2B DAPK3 DENND5A EGFR FADD FEZ1 FEZ2 FRS2 FYN GLRX3 GRB14 GRM5 GSK3A GSK3B H1-1 H1-5 HABP4 HDAC6 HRAS IKBKB IL4R IRAK1 IRS1 IRS4 JAK1 KRT10 LRRK2 MAP2K1 MAP2K5 MAPK1 MAPK3 MAPK7 MAPT MARCKS MBP NCF1 NCL NCOA3 NFATC2 NMT2 NUMB PARD6A PARD6B PARD6G PAWR PDLIM7 PDPK1 PEBP1 PIAS4 PPP1R14A PPP3CA PRG2 PRKCA PRKCD PSEN1 RAF1 RELA RHOA SLC39A1 SP1 SQSTM1 SRC STAT6 STUB1 TIAM1 TRAF6 UTP14A WWC1 YWHAB YWHAQ YWHAZ ZNF71
Entrez ID 8650 5590
HPRD ID 04767 01504
Ensembl ID ENSG00000133961 ENSG00000067606
Uniprot IDs A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757 Q05513
PDB IDs 5NJJ 5NJK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?