NUMB and PRKCB

  • Number of citations of the paper that reports this interaction (PubMedID 17203073)
  • 91
  • Data Source:
  • HPRD (in vitro)

NUMB

PRKCB

Description NUMB endocytic adaptor protein protein kinase C beta
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 31194737)
  • Blood protein levels ( 30072576)
  • Bone mineral content ( 31790847)
  • Cadmium levels ( 26025379)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Primary biliary cholangitis ( 28062665)
  • Sleep duration ( 30531941)
  • Ulcerative colitis ( 28067908)
Interacting Genes 33 interacting genes: AP2A1 AP2A2 APP DNAJC5 DPYSL2 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 TERF2 87 interacting genes: AFAP1 AKT1 ANXA2 ANXA7 BLVRA BMPR2 BTK CARD11 CASR CD5 CHAT CHUK CISH CSF2RB CYTH2 DAB2 DVL2 EGFR EIF4E EIF6 EP300 EPB41 FBXO7 GABRB2 GABRG2 GAP43 GCNT1 GJA1 GNA12 GNA13 GRIN1 GRIN2B GRIN2D GRK2 GRM5 GSK3A GSK3B H1-0 H1-1 H1-5 H3C1 HABP4 HSPA4 IBTK IFNAR2 IKBKB IKBKG ITGB2 ITGB7 KIT LMNB1 LST1 MAPK6 MAPT MARCKS MBP MKI67 NCF1 NRGN NUMB PA2G4 PDLIM5 PDLIM7 PDPK1 PEBP1 PPP1CA PPP2CB PTPA PTPN11 RACK1 RASGRP3 RB1 RGS2 RIPK4 RRAD SDC2 SPTAN1 STXBP1 SYT6 TERF1 TIAM1 TINF2 TOP2A TRIM41 VTN YWHAG ZMYND8
Entrez ID 8650 5579
HPRD ID 04767 01499
Ensembl ID ENSG00000133961 ENSG00000166501
Uniprot IDs A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757 P05771
PDB IDs 5NJJ 5NJK 2I0E
Enriched GO Terms of Interacting Partners?
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