Wiki-CORONA
About
Search
Browse
Data Sources
People
Funding
Advanced Search
AQP1 and TRAF1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
AQP1
TRAF1
Description
aquaporin 1 (Colton blood group)
TNF receptor associated factor 1
Image
GO Annotations
Cellular Component
Cell
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Cytoplasm
Cytosol
Cytoplasmic Side Of Plasma Membrane
Plasma Membrane Receptor Complex
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Response To Drug
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Apoptotic Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein-containing Complex Assembly
Protein K63-linked Ubiquitination
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Drugs
Acetazolamide
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Celiac disease or Rheumatoid arthritis (
21383967
)
Lymphocyte counts (
27863252
)
Pulse pressure (
30578418
)
Rheumatoid arthritis (
30891314
24782177
23143596
24390342
20453842
19503088
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
Interacting Genes
44 interacting genes:
ADAMTSL4
CCDC136
CCDC57
CCDC85B
CEP44
CREB3
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IHO1
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
LMNA
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NLA
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
186 interacting genes:
A1CF
ABHD17A
ACTN3
AKAP17A
AQP1
ARNT2
ARSJ
BARD1
BCAS2
BCL6
BEX2
BEX3
BIRC2
BIRC3
C1orf109
C1orf216
C2CD6
CARHSP1
CASP10
CASP3
CASP6
CASP8
CCDC116
CCDC120
CCDC146
CCDC198
CCHCR1
CD40
CDCA3
CDKN1A
CDKN2B
CFLAR
CHCHD3
CNTRL
COX5B
CRYGA
CYB5R2
DEPTOR
DGCR6
DMRT3
DOK3
EDAR
EHHADH
EWSR1
FAM161A
FAM86C1P
FBF1
FBXL18
FOSL2
GATA1
GATA2
GATAD2B
GEM
GFI1B
GIT2
GLRX3
GMCL2
GNG5
GOLGA2
GORASP2
GRAP2
HAUS1
HEY2
HIVEP3
HMG20B
HOXA1
HOXD12
IKBKB
JOSD1
KIAA1217
KIF1A
KLHL38
KPNA2
LATS1
LCOR
LNX1
LNX2
LTBR
MACIR
MAP3K14
MAP6
MAPRE2
METTL17
MORN3
MOS
MYEF2
NEBL
NOL4L-DT
NTAQ1
NUFIP2
NUP58
OLIG3
PBX3
PDE4D
PHF21A
PIN1
PKN1
PLAC8
PLEKHN1
POM121L4P
POP5
PPP1R13B
PRDM7
PRKAB2
PSMA1
PSMB1
QRICH1
RASAL2
RASSF5
RBCK1
RBM41
RBM45
RIPK1
RIPK2
RNF31
RTP5
SCNM1
SDCBP2
SH3GLB2
SHARPIN
SHFL
SIK3
SLC25A48
SLC25A6
SNW1
SPG21
SPOP
SRC
SSC5D
STK3
SUMO2
SYCE1
TANK
TBC1D16
TCL1A
TEAD4
TFAP4
TFPT
THAP7
TICAM1
TIFA
TLE5
TNFAIP3
TNFRSF11A
TNFRSF12A
TNFRSF14
TNFRSF17
TNFRSF18
TNFRSF19
TNFRSF1A
TNFRSF1B
TNFRSF4
TNFRSF8
TNFRSF9
TNFSF9
TRADD
TRAF2
TRAF3IP2
TRAF6
TRAIP
TRIM23
TRIM37
TRIM42
TRPV6
TSSC4
USP7
WAC
ZBTB1
ZBTB16
ZC2HC1C
ZFYVE21
ZFYVE26
ZNF124
ZNF20
ZNF250
ZNF417
ZNF440
ZNF502
ZNF512B
ZNF564
ZNF572
ZNF581
ZNF587
ZNF662
ZNF688
ZNF697
Entrez ID
358
7185
HPRD ID
00140
03418
Ensembl ID
ENSG00000240583
ENSG00000056558
Uniprot IDs
A0A024RA31
P29972
Q13077
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
3M0D
5E1T
5H10
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?