SMARCC2 and TAF15

Number of citations of the paper that reports this interaction (PubMedID 30962207)
2

Data Source:
BioGRID (pull down)

		SMARCC2	TAF15
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	TATA-box binding protein associated factor 15
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS		Asthma ( 31619474)	Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP	22 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 POLR2C POLR2E POLR2G PRMT8 SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		6601	8148
HPRD ID		03437	09031
Ensembl ID		ENSG00000139613	ENSG00000270647
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	Q92804
PDB IDs			2MMY
Enriched GO Terms of Interacting Partners?
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