ID1 and TCF12

Number of citations of the paper that reports this interaction (PubMedID 9242638)
70

Data Source:
HPRD (two hybrid)

		ID1	TCF12
Description		inhibitor of DNA binding 1, HLH protein	transcription factor 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Centrosome	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Protein C-terminus Binding Identical Protein Binding Protein Self-association Protein Dimerization Activity Protein N-terminus Binding Proteasome Binding Transcription Regulator Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding CAMP Response Element Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding HMG Box Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Endothelial Cell Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Brain Development Heart Development Negative Regulation Of Transcription By Transcription Factor Localization Positive Regulation Of Gene Expression Cell Differentiation BMP Signaling Pathway Protein Destabilization Negative Regulation Of Protein Binding Positive Regulation Of Actin Filament Bundle Assembly Circadian Regulation Of Gene Expression Collagen Metabolic Process Cell-abiotic Substrate Adhesion Negative Regulation Of Apoptotic Process Regulation Of MAPK Cascade Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Response To Antibiotic Blood Vessel Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Negative Regulation Of Dendrite Morphogenesis Lung Morphogenesis Lung Vasculature Development Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Cold-induced Thermogenesis Cellular Response To Peptide Cellular Response To Dopamine Positive Regulation Of Nucleic Acid-templated Transcription Cellular Response To Nerve Growth Factor Stimulus	Regulation Of Transcription By RNA Polymerase II Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Oncogene Induced Senescence NGF-stimulated transcription	Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alcohol consumption (drinks per week) ( 30643258) Body mass index ( 28892062) Glaucoma (primary open-angle) ( 29891935) Male-pattern baldness ( 28196072) Mean platelet volume ( 27863252) Type 2 diabetes ( 30297969)
Interacting Genes		22 interacting genes: AAR2 APPL1 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MYF5 MYF6 MYOD1 MYOG POFUT1 PSMD4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4	59 interacting genes: ACTB ADAM10 ARMC8 ASCL4 BCL2L10 BMERB1 BMF C1orf109 CDKN2C CFAP206 CRCP CREBBP DGCR6 EDRF1 EP300 FRMD6 HAND1 HOPX ID1 ID2 ID3 LYSMD1 MAPK6 MAPKBP1 MLLT6 MORN4 MSC MYF6 NAGK OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS1 RNASEL RSL24D1 RUNX1T1 SCG3 SLC12A1 SLC24A1 SOX10 SOX8 SPG21 SPTBN5 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28 YKT6 ZNF688
Entrez ID		3397	6938
HPRD ID		08980	02725
Ensembl ID		ENSG00000125968	ENSG00000140262
Uniprot IDs		P41134	A0A024R5T1 A0A024R5Z0 F5GY10 Q99081
PDB IDs			2KNH 4JOL
Enriched GO Terms of Interacting Partners?
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