ID1 and RUNX1T1

Number of citations of the paper that reports this interaction (PubMedID 11591653)
41

Data Source:
HPRD (in vivo)

		ID1	RUNX1T1
Description		inhibitor of DNA binding 1, HLH protein	RUNX1 partner transcriptional co-repressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Centrosome	Nucleus Nucleoplasm Nuclear Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Protein C-terminus Binding Identical Protein Binding Protein Self-association Protein Dimerization Activity Protein N-terminus Binding Proteasome Binding Transcription Regulator Activity	DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Endothelial Cell Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Brain Development Heart Development Negative Regulation Of Transcription By Transcription Factor Localization Positive Regulation Of Gene Expression Cell Differentiation BMP Signaling Pathway Protein Destabilization Negative Regulation Of Protein Binding Positive Regulation Of Actin Filament Bundle Assembly Circadian Regulation Of Gene Expression Collagen Metabolic Process Cell-abiotic Substrate Adhesion Negative Regulation Of Apoptotic Process Regulation Of MAPK Cascade Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Response To Antibiotic Blood Vessel Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Negative Regulation Of Dendrite Morphogenesis Lung Morphogenesis Lung Vasculature Development Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Cold-induced Thermogenesis Cellular Response To Peptide Cellular Response To Dopamine Positive Regulation Of Nucleic Acid-templated Transcription Cellular Response To Nerve Growth Factor Stimulus	Generation Of Precursor Metabolites And Energy Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Oncogene Induced Senescence NGF-stimulated transcription
Drugs
Diseases			Acute myeloid leukemia (AML)
GWAS		Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)	Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		22 interacting genes: AAR2 APPL1 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MYF5 MYF6 MYOD1 MYOG POFUT1 PSMD4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4	52 interacting genes: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CBY2 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 IHO1 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRKAR2A SIN3A SPEN SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		3397	862
HPRD ID		08980	00590
Ensembl ID		ENSG00000125968	ENSG00000079102
Uniprot IDs		P41134	A0A087WWT6 A0A0A0MSU1 B2R6I9 Q06455 W8FW32
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?
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