TCF12 and C1orf109

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TCF12	C1orf109
Description		transcription factor 12	chromosome 1 open reading frame 109
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding CAMP Response Element Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding HMG Box Domain Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alcohol consumption (drinks per week) ( 30643258) Body mass index ( 28892062) Glaucoma (primary open-angle) ( 29891935) Male-pattern baldness ( 28196072) Mean platelet volume ( 27863252) Type 2 diabetes ( 30297969)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		59 interacting genes: ACTB ADAM10 ARMC8 ASCL4 BCL2L10 BMERB1 BMF C1orf109 CDKN2C CFAP206 CRCP CREBBP DGCR6 EDRF1 EP300 FRMD6 HAND1 HOPX ID1 ID2 ID3 LYSMD1 MAPK6 MAPKBP1 MLLT6 MORN4 MSC MYF6 NAGK OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS1 RNASEL RSL24D1 RUNX1T1 SCG3 SLC12A1 SLC24A1 SOX10 SOX8 SPG21 SPTBN5 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28 YKT6 ZNF688	46 interacting genes: C1orf94 CBY2 CEP55 CINP CRX CSNK2A1 GOLGA2 IHO1 IKZF1 IKZF3 KATNAL1 KIFC3 KRT13 KRT19 KRT31 KRT40 LDOC1 LZTS2 MAP7D1 MEOX2 MKRN2 MTUS2 NECAB2 PDE4DIP PHC2 PLK4 PPP1R12C REL RINT1 RNF41 SDCBP SPAG5 STX11 TADA2A TCF12 TCF4 TFIP11 TLE5 TRAF1 TRIM27 TRIM42 TRIM54 USHBP1 VPS52 ZBED1 ZNF398
Entrez ID		6938	54955
HPRD ID		02725	07918
Ensembl ID		ENSG00000140262	ENSG00000116922
Uniprot IDs		A0A024R5T1 A0A024R5Z0 F5GY10 Q99081	B4DRQ5 B7Z9X8 Q9NX04
PDB IDs		2KNH 4JOL
Enriched GO Terms of Interacting Partners?
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