HNRNPAB and PTBP2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		HNRNPAB	PTBP2
Description		heterogeneous nuclear ribonucleoprotein A/B	polypyrimidine tract binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex Ribonucleoprotein Complex	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body
	Molecular Function	DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Binding MRNA Binding
	Biological Process	Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)
Interacting Genes		17 interacting genes: ACTB DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 RBFOX2 TP63 USP19 YWHAG	20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1
Entrez ID		3182	58155
HPRD ID		04067	12233
Ensembl ID		ENSG00000197451	ENSG00000117569
Uniprot IDs		Q99729	B4DSS8 B4DSU5 Q9UKA9
PDB IDs		3S7R	2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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