HNRNPA2B1 and SREK1

Number of citations of the paper that reports this interaction (PubMedID 14559993)
14

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		HNRNPA2B1	SREK1
Description		heterogeneous nuclear ribonucleoprotein A2/B1	splicing regulatory glutamic acid and lysine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding Single-stranded Telomeric DNA Binding Pre-mRNA Intronic Binding G-rich Strand Telomeric DNA Binding N6-methyladenosine-containing RNA Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus Viral Process RNA Metabolic Process Primary MiRNA Processing Interleukin-12-mediated Signaling Pathway G-quadruplex DNA Unwinding Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Transport Regulation Of RNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomerase RNA Reverse Transcriptase Activity MiRNA Transport	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Copper Artenimol
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		19 interacting genes: CDKN2A CSNK2A1 CSNK2B ERG ESR1 H3-4 HIPK3 HNRNPL HSPB1 LIG4 MAP4K2 MCPH1 NR4A1 SNRNP70 SREK1 TTF2 VHL YAE1 ZMYM2	55 interacting genes: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RACK1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2
Entrez ID		3181	140890
HPRD ID		02526	18043
Ensembl ID		ENSG00000122566	ENSG00000153914
Uniprot IDs		P22626	Q8WXA9
PDB IDs		1X4B 5EN1 5HO4 5WWE 5WWF 5WWG
Enriched GO Terms of Interacting Partners?
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