FOXA3 and ALX4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		FOXA3	ALX4
Description		forkhead box A3	ALX homeobox 4
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GO Annotations	Cellular Component	Nuclear Chromatin Cell Nucleus Nucleoplasm Actin Cytoskeleton	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Factor Binding Protein Domain Specific Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding HMG Box Domain Binding
	Biological Process	Cellular Glucose Homeostasis Chromatin Organization Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Cellular Response To Starvation Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Skeletal System Development Hair Follicle Development Muscle Organ Development Post-embryonic Development Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Digit Morphogenesis Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Digestive Tract Development Embryonic Skeletal System Morphogenesis Roof Of Mouth Development
Pathways		Regulation of gene expression in beta cells
Drugs
Diseases			Frontonasal dysplasia Enlarged parietal foramina/cranium bifidum
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Sum eosinophil basophil counts ( 27863252)	Blood pressure measurement (high sodium intervention) ( 24165912) Cadmium levels ( 26025379) Excessive hairiness ( 29895819) Gout ( 22179738) Male-pattern baldness ( 29146897 27182965) Monobrow ( 27182965) Response to antidepressants in depression ( 29998114) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		5 interacting genes: ALX4 HMGB1 PPARA TLE1 TLE2	12 interacting genes: ALX1 CEBPE EMX1 FOXA3 GATA4 HOXA3 HOXB13 HOXB6 HOXD3 LEF1 SOX10 SOX2
Entrez ID		3171	60529
HPRD ID		03802	05661
Ensembl ID		ENSG00000170608	ENSG00000052850
Uniprot IDs		A0A024R0R3 P55318	Q9H161
PDB IDs		1VTN	2M0C
Enriched GO Terms of Interacting Partners?
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