FOXA2 and MIP

Number of citations of the paper that reports this interaction (PubMedID 12642491)
18

Data Source:
HPRD (in vitro)

		FOXA2	MIP
Description		forkhead box A2	major intrinsic protein of lens fiber
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cell Junction	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Factor Binding Protein Domain Specific Binding Transcription Regulatory Region DNA Binding	Structural Constituent Of Eye Lens Calmodulin Binding Water Channel Activity
	Biological Process	Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cell Fate Specification Chromatin Organization Regulation Of Transcription By RNA Polymerase II Adult Locomotory Behavior Anatomical Structure Morphogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Regulation Of Blood Coagulation Endocrine Pancreas Development Negative Regulation Of Glucokinase Activity Positive Regulation Of Embryonic Development Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Interleukin-6 Dopaminergic Neuron Differentiation Primitive Streak Formation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Gastrulation Negative Regulation Of Detection Of Glucose	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Regulation of gene expression in beta cells	Passive transport by Aquaporins
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 25784220) Birth weight ( 31043758) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting plasma glucose ( 25187374 20152958) Gout ( 22179738) Hypothyroidism ( 27182965) Male-pattern baldness ( 22693459 27182965) Monobrow ( 27182965) Type 2 diabetes ( 30054458) Vitamin D levels ( 26704534)	Axial length ( 24144296)
Interacting Genes		9 interacting genes: EN2 GSC HOXA5 LHX1 MIP NCOA1 ONECUT1 OTX2 TLE1	10 interacting genes: CALM1 CRYAA CRYAB CRYBB2 CRYGC FOXA2 GJA3 GJA8 LMNA PRKACA
Entrez ID		3170	4284
HPRD ID		02618	01098
Ensembl ID		ENSG00000125798	ENSG00000135517
Uniprot IDs		B0ZTD4 Q9Y261	P30301
PDB IDs		5X07
Enriched GO Terms of Interacting Partners?
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