FOXA2 and HOXA5

Number of citations of the paper that reports this interaction (PubMedID 12642491)
18

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		FOXA2	HOXA5
Description		forkhead box A2	homeobox A5
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cell Junction	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Factor Binding Protein Domain Specific Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cell Fate Specification Chromatin Organization Regulation Of Transcription By RNA Polymerase II Adult Locomotory Behavior Anatomical Structure Morphogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Regulation Of Blood Coagulation Endocrine Pancreas Development Negative Regulation Of Glucokinase Activity Positive Regulation Of Embryonic Development Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Interleukin-6 Dopaminergic Neuron Differentiation Primitive Streak Formation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Gastrulation Negative Regulation Of Detection Of Glucose	Respiratory System Process Anterior/posterior Pattern Specification Positive Regulation Of Receptor Biosynthetic Process Cell Migration Negative Regulation Of Angiogenesis Thyroid Gland Development Regulation Of Mammary Gland Epithelial Cell Proliferation Multicellular Organism Growth Positive Regulation Of Apoptotic Process Positive Regulation Of Myeloid Cell Differentiation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Lung Alveolus Development Embryonic Skeletal System Morphogenesis Bronchiole Development Epithelial Tube Branching Involved In Lung Morphogenesis Lung Goblet Cell Differentiation Lung-associated Mesenchyme Development Trachea Cartilage Morphogenesis Intestinal Epithelial Cell Maturation Mesenchymal-epithelial Cell Signaling Mammary Gland Epithelial Cell Differentiation Mammary Gland Alveolus Development Cell-cell Signaling Involved In Mammary Gland Development
Pathways		Regulation of gene expression in beta cells
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 25784220) Birth weight ( 31043758) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting plasma glucose ( 25187374 20152958) Gout ( 22179738) Hypothyroidism ( 27182965) Male-pattern baldness ( 22693459 27182965) Monobrow ( 27182965) Type 2 diabetes ( 30054458) Vitamin D levels ( 26704534)	Chronic venous disease ( 28374850)
Interacting Genes		9 interacting genes: EN2 GSC HOXA5 LHX1 MIP NCOA1 ONECUT1 OTX2 TLE1	12 interacting genes: CDX4 DDIT3 DNMT3L FOXA2 FOXO1 GTF2A1L MEIS1 PBX1 PRMT6 SMAD1 TWIST1 ZNF408
Entrez ID		3170	3202
HPRD ID		02618	00840
Ensembl ID		ENSG00000125798	ENSG00000106004
Uniprot IDs		B0ZTD4 Q9Y261	P20719
PDB IDs		5X07
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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