HIVEP1 and HPD

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HIVEP1	HPD
Description		HIVEP zinc finger 1	4-hydroxyphenylpyruvate dioxygenase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Body	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	4-hydroxyphenylpyruvate Dioxygenase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	L-phenylalanine Catabolic Process Tyrosine Catabolic Process Oxidation-reduction Process
Pathways			Tyrosine catabolism
Drugs			Nitisinone (1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone
Diseases			Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Alcohol and nicotine co-dependence ( 22488850) Body mass index ( 28892062 25673413 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Metabolite levels ( 23823483) Takayasu arteritis ( 25604533)	Obesity-related traits ( 23251661) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407 21572414)
Interacting Genes		37 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A CLK1 DNAJA1 EMG1 GAA GSDMB HPD HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A RIDA SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 SRPK2 STAT3 TMEM176A	4 interacting genes: CDKN1A HIVEP1 IKBKG RIDA
Entrez ID		3096	3242
HPRD ID		01925	02041
Ensembl ID		ENSG00000095951	ENSG00000158104
Uniprot IDs		P15822	P32754
PDB IDs		1BBO 3ZNF 4ZNF	3ISQ 5EC3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?