HPD and RIDA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HPD	RIDA
Description		4-hydroxyphenylpyruvate dioxygenase	reactive intermediate imine deaminase A homolog
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Cytosol Extracellular Exosome
	Molecular Function	4-hydroxyphenylpyruvate Dioxygenase Activity Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Endoribonuclease Activity, Producing 3'-phosphomonoesters Deaminase Activity Long-chain Fatty Acid Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	L-phenylalanine Catabolic Process Tyrosine Catabolic Process Oxidation-reduction Process	Kidney Development MRNA Catabolic Process Brain Development Negative Regulation Of Translation L-threonine Catabolic Process To Glycine Lung Development Response To Lipid Negative Regulation Of Epithelial Cell Proliferation MRNA Destabilization G1 To G0 Transition RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Organonitrogen Compound Catabolic Process Response To Salt
Pathways		Tyrosine catabolism	Threonine catabolism
Drugs		Nitisinone (1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone	Benzoic Acid
Diseases		Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Obesity-related traits ( 23251661) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407 21572414)
Interacting Genes		4 interacting genes: CDKN1A HIVEP1 IKBKG RIDA	9 interacting genes: DEAF1 HIVEP1 HPD MDM2 MT-CO2 SERPINA5 SPEN TMEM176A TRIB3
Entrez ID		3242	10247
HPRD ID		02041	03924
Ensembl ID		ENSG00000158104	ENSG00000132541
Uniprot IDs		P32754	A0A024R9H2 P52758
PDB IDs		3ISQ 5EC3	1ONI
Enriched GO Terms of Interacting Partners?
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