HIVEP1 and GSDMB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HIVEP1	GSDMB
Description		HIVEP zinc finger 1	gasdermin B
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Body	Cellular_component Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Phosphatidylserine Binding Molecular_function Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Biological_process Defense Response To Bacterium Pyroptosis
Pathways
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Body mass index ( 28892062 25673413 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Metabolite levels ( 23823483) Takayasu arteritis ( 25604533)	Adult asthma ( 30787307) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 21804549 31361310 30929738 20860503 31619474 29273806 28461288) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738 27611488 24241537 29273806) Asthma (time to onset) ( 27130862) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Atrial fibrillation ( 30061737) Bronchial hyperresponsiveness in asthma ( 27439200) Cervical cancer ( 23817570) Crohn's disease ( 28067908) Dermatomyositis or juvenile dermatomyositis ( 26362759) Feeling miserable ( 29500382) Fractional exhaled nitric oxide (childhood) ( 24315451) IgM levels ( 28628107) Inflammatory bowel disease ( 28067908 23128233) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Monocyte percentage of white cells ( 27863252) Primary biliary cholangitis ( 23000144 20639880 30643196) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Self-reported allergy ( 23817569) Subcutaneous adipose tissue ( 27918534) Systemic lupus erythematosus ( 26502338) Systemic sclerosis ( 28314753 31672989) Type 1 diabetes ( 25751624) Ulcerative colitis ( 28067908) White blood cell count ( 21738480)
Interacting Genes		37 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A CLK1 DNAJA1 EMG1 GAA GSDMB HPD HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A RIDA SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 SRPK2 STAT3 TMEM176A	8 interacting genes: AGT APP CLK1 HIVEP1 IGFBP2 ORM1 PEBP1 SERPINA1
Entrez ID		3096	55876
HPRD ID		01925	17082
Ensembl ID		ENSG00000095951	ENSG00000073605
Uniprot IDs		P15822	Q8TAX9
PDB IDs		1BBO 3ZNF 4ZNF	5TIB 5TJ2 5TJ4
Enriched GO Terms of Interacting Partners?
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